Thrombotic Diseases

Thrombotic diseases encompass a spectrum of conditions characterized by pathological blood clot formation (thrombosis) in arterial or venous vessels. Thrombotic events is the main cause of myocardial infarction, stroke and venous thrombo-embolism globally, accounting for one-quarter of deaths globally each year. Risk factors include advanced age, obesity, physical inactivity, and major surgery, while medical conditions such as metabolic disorders, atrial fibrillation and cancer significantly increase thrombotic risk. Notably, metabolic disorders such as hyperlipidemia (particularly elevated levels of cholesterol and triglycerides) can promote thrombosis by inducing endothelial dysfunction, atherosclerotic vascular disease and creating a prothrombotic state.

Dyslipidemia
Dyslipidemia is a condition characterized by abnormal levels of any or all lipids (e.g.triglycerides, cholesterol, phospholipids) or liproproteins in the blood. Globally, the prevalence of dyslipidemia in adults is estimated at around 40%, affecting approximately 3.0 billion individuals each year.